ATG10

Autophagy-related protein 10 is a protein that in humans is encoded by the ATG10 gene.

ATG10
Identifiers
Aliases	ATG10, APG10, APG10L, pp12616, autophagy related 10
External IDs	OMIM: 610800; MGI: 1914045; HomoloGene: 12036; GeneCards: ATG10; OMA:ATG10 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) Band 5q14.1-q14.2 Start 81,972,023 bp End 82,276,857 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 C3 Start 91,083,475 bp End 91,372,087 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad islet of Langerhans monocyte ganglionic eminence tibial arteries skin of abdomen gastrocnemius muscle right coronary artery stromal cell of endometrium Top expressed in interventricular septum Epithelium of choroid plexus epithelium of small intestine myocardium of ventricle intercostal muscle right kidney extraocular muscle facial motor nucleus Rostral migratory stream lumbar spinal ganglion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function Atg12 transferase activity transferase activity Cellular component cytoplasm cytosol intracellular anatomical structure Biological process autophagy protein transport protein modification by small protein conjugation macroautophagy positive regulation of protein modification process ER overload response protein lipidation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83734 66795 Ensembl ENSG00000152348 ENSMUSG00000021619 UniProt Q9H0Y0 Q8R1P4 RefSeq (mRNA) NM_001131028 NM_031482 NM_025770 RefSeq (protein) NP_001124500 NP_113670 NP_080046 NP_001391846 NP_001391847 NP_001391848 NP_001391849 NP_001391850 NP_001391851 NP_001391852 NP_001391854 NP_001391855 NP_001391856 NP_001391857 Location (UCSC) Chr 5: 81.97 – 82.28 Mb Chr 13: 91.08 – 91.37 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

External links

• Human ATG10 genome location and ATG10 gene details page in the UCSC Genome Browser.

Further reading

• Feldman RD, Hunninghake GW, McArdle WL (1987). "Beta-adrenergic-receptor-mediated suppression of interleukin 2 receptors in human lymphocytes". J. Immunol. 139 (10): 3355–9. doi:10.4049/jimmunol.139.10.3355. PMID 2890687.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mizushima N, Yoshimori T, Ohsumi Y (2003). "Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method". FEBS Lett. 532 (3): 450–4. doi:10.1016/S0014-5793(02)03739-0. PMID 12482611. S2CID 37247321.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.