A. I. duPont may refer to:
- Alfred I. duPont (1864 – 1935), American industrialist, financier and philanthropist
- Alexis I. duPont High School, public high school located in Greenville, Delaware, USA, a suburb of Wilmington
- Alfred I. duPont Hospital for Children
This disambiguation page lists articles associated with the title A. I. duPont.
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