Labdatriene synthase (EC 4.2.3.99, OsKSL10 (gene)) is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase ((12E)-9α-labda-8(17),12,14-triene-forming).[1] This enzyme catalyses the following chemical reaction

Labdatriene synthase
Identifiers
EC no.4.2.3.99
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
9α-copalyl diphosphate (12E)-9α-labda-8(17),12,14-triene + diphosphate

The enzyme from rice (Oryza sativa) also produces ent-sandaracopimara-8(14),15-diene from ent-copalyl diphosphate.

References

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  1. ^ Morrone D, Hillwig ML, Mead ME, Lowry L, Fulton DB, Peters RJ (May 2011). "Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals". The Biochemical Journal. 435 (3): 589–95. doi:10.1042/bj20101429. PMC 3723722. PMID 21323642.
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