8-Hydroxy-5-deazaflavin:NADPH oxidoreductase

8-Hydroxy-5-deazaflavin:NADPH oxidoreductase (EC 1.5.1.40, 8-OH-5dFl:NADPH oxidoreductase) is an enzyme with systematic name reduced coenzyme F420:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

8-hydroxy-5-deazaflavin:NADPH oxidoreductase
Identifiers
EC no.1.5.1.40
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IntEnzIntEnz view
BRENDABRENDA entry
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MetaCycmetabolic pathway
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NCBIproteins
reduced coenzyme F420 + NADP+ coenzyme F420 + NADPH + H+

The enzyme requires the 5-deazaflavin structure, as well as an 8-hydroxy group in the substrate.

References

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  1. ^ Eker AP, Hessels JK, Meerwaldt R (January 1989). "Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus". Biochimica et Biophysica Acta (BBA) - General Subjects. 990 (1): 80–6. doi:10.1016/s0304-4165(89)80015-7. PMID 2492438.
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