3D printed medicine

3D printed medicine refers to medicine manufactured using 3D printing technology. It includes 3D printed medications or 3D printed drugs, which are medications that are manufactured using 3D printing technology. 3D printing enables the creation of customized and precise dosage forms tailored to the specific needs of patients. Various technologies have been developed to create 3D-printed medications.

Description edit

Medicine manufactured using 3D printing technology is known as 3D printed medicine.

Applications edit

3D drug printing edit

3D printed medication or 3D printed drug refers to a medication that is manufactured using 3D printing technology which is an additive manufacturing approach.^[1] 3D printing enables the creation of customized and precise dosage forms tailored to the specific needs of patients. As such, the field of 3D drug printing is a part of personalized or precision medicine. Furthermore, 3D drug printing is a sub-field of pharmaceutics.

The most common application of 3D printing in pharmaceuticals is the production of pills or tablets. 3D printing offers precise dosing, the ability to design tablets with improved release profiles, and the capability to combine multiple medications into a single tablet.^[2] Current developments primarily focus on 3D printing drugs for pediatric, geriatric, psychiatry, and neurology patients, where dosage adjustments are often necessary based on a patient's condition, and patient adherence is a challenge.^[3]^[4] The first 3D-printed tablet to receive FDA approval was Spritam (levetiracetam), an anti-epileptic medication.^[5]

Technologies edit

Various technologies have been developed to create 3D-printed medications, including:

References edit

^ Capel, Andrew J.; Rimington, Rowan P.; Lewis, Mark P.; Christie, Steven D. R. (21 November 2018). "3D printing for chemical, pharmaceutical, and biological applications". Nature Reviews Chemistry. 2 (12): 422–436. doi:10.1038/s41570-018-0058-y. S2CID 187087516.
^ Wang, S; Chen, X; Han, X; Hong, X; Li, X; Zhang, H; Li, M; Wang, Z; Zheng, A (26 January 2023). "A Review of 3D Printing Technology in Pharmaceutics: Technology and Applications, Now and Future". Pharmaceutics. 15 (2): 416. doi:10.3390/pharmaceutics15020416. PMC 9962448. PMID 36839738.
^ M, Michael (29 August 2023). "Research Begins On 3D Printed Drugs For Pediatric Care". 3Dnatives.
^ Shaikhnag, Ada (11 October 2023). "MB Therapeutics uses 3D printing to create personalized medicine for children". 3D Printing Industry.
^ "First 3D-printed pill". Nature Biotechnology. 33 (10): 1014. October 2015. doi:10.1038/nbt1015-1014a. PMID 26448072. S2CID 28321356.

[1] Capel, Andrew J.; Rimington, Rowan P.; Lewis, Mark P.; Christie, Steven D. R. (21 November 2018). "3D printing for chemical, pharmaceutical, and biological applications". Nature Reviews Chemistry. 2 (12): 422–436. doi:10.1038/s41570-018-0058-y. S2CID 187087516.

[2] Wang, S; Chen, X; Han, X; Hong, X; Li, X; Zhang, H; Li, M; Wang, Z; Zheng, A (26 January 2023). "A Review of 3D Printing Technology in Pharmaceutics: Technology and Applications, Now and Future". Pharmaceutics. 15 (2): 416. doi:10.3390/pharmaceutics15020416. PMC 9962448. PMID 36839738.

[3] M, Michael (29 August 2023). "Research Begins On 3D Printed Drugs For Pediatric Care". 3Dnatives.

[4] Shaikhnag, Ada (11 October 2023). "MB Therapeutics uses 3D printing to create personalized medicine for children". 3D Printing Industry.

[5] "First 3D-printed pill". Nature Biotechnology. 33 (10): 1014. October 2015. doi:10.1038/nbt1015-1014a. PMID 26448072. S2CID 28321356.

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