3-Phosphoglyceric acid (3PG) is the conjugate acid of glycerate 3-phosphate (GP). The glycerate is a biochemically significant metabolic intermediate in both glycolysis and the Calvin cycle. This anion is often termed as PGA when referring to the Calvin cycle. In the Calvin cycle, 3-phosphoglycerate is the product of the spontaneous scission of an unstable 6-carbon intermediate formed upon CO2 fixation. Thus, two equivalents of 3-phosphoglycerate are produced for each molecule of CO2 that is fixed.
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||186.06 g/mol|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Compound C00236 at KEGG Pathway Database. Enzyme 188.8.131.52 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 184.108.40.206 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.
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In the light-independent reactions (also known as the Calvin cycle), two 3-phosphoglycerate molecules are synthesized, one of which continues through the Calvin cycle to be regenerated to RuBP and the other is reduced to form one molecule of glyceraldehyde 3-phosphate (G3P). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.