The 2016 Samarkand Challenger was a professional tennis tournament played on clay courts. It was the 20th edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Samarkand, Uzbekistan between 9 and 14 May 2016.
| 2016 Samarkand Challenger | |
|---|---|
| Date | 9–14 May |
| Edition | 20th |
| Draw | 32S / 16D |
| Prize money | $50,000 |
| Surface | Clay |
| Location | Samarkand, Uzbekistan |
| Champions | |
| Singles | |
 Karen Khachanov | |
| Doubles | |
Denis Matsukevich /  Andrei Vasilevski | |
Singles main-draw entrants edit
Seeds edit
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| RUS
|
Karen Khachanov | 125 | 1 |
 MDA
|
Radu Albot | 143 | 2 |
 ISR
|
Amir Weintraub | 192 | 3 |
 ESP
|
Jordi Samper-Montaña | 216 | 4 |
 UZB
|
Farrukh Dustov | 220 | 5 |
 KAZ
|
Dmitry Popko | 225 | 6 |
 SRB
|
Nikola Milojević | 233 | 7 |
| ESP
|
Enrique López Pérez | 235 | 8 |
- 1 Rankings are as of May 2, 2016.
Other entrants edit
The following players received wildcards into the singles main draw:
Sanjar Fayziev- Temur Ismailov
- Shonigmatjon Shofayziyev
- Pavel Tsoy
The following players received entry from the qualifying draw:
Bar Tzuf Botzer
Mikhail Elgin- Markos Kalovelonis
Francesco Vilardo
Champions edit
Singles edit
- Karen Khachanov def.
Rubén Ramírez Hidalgo, 6–1, 6–7(6–8), 6–1
Doubles edit
- Denis Matsukevich /
Andrei Vasilevski def. 
Hsieh Cheng-peng / Yang Tsung-hua, 6–4, 5–7, [10–5]
