The 1888 Missouri gubernatorial election was held on November 6, 1888 and resulted in a victory for the Democratic nominee, Mayor of St. Louis David R. Francis, over the Republican candidate Elbert E. Kimball, Union Labor candidate Ahira Manring, and Prohibition candidate Frank M. Lowe.
|Democratic||David R. Francis||255,764||49.36||-0.69|
|Republican||Elbert E. Kimball||242,531||46.81||-0.74|
|Union Labor Party||Ahira Manring||15,438||2.98||+2.98|
|Prohibition||Frank M. Lowe||4,389||0.85||+0.85|