157 may refer to:

  • 157 (year)
  • 157 (number)
  • UFC 157, a mixed martial arts event held by the Ultimate Fighting Championship
  • ONE 157, a combat sport event produced by ONE Championship
  • Radical 157, one of the 20 Kangxi radicals composed of 7 strokes meaning "foot"
  • NGC 157, an intermediate spiral galaxy in the constellation of Cetus
  • 157 series, a DC electric multiple unit train type
  • Tatra 157, the prototype version of the Tatra 815