Diede de Groot defeated the defending champion Yui Kamiji in the final, 6–3, 6–7(4–7), 7–6(10–4) to win the women's singles wheelchair tennis title at the 2021 Australian Open. It was the first step in an eventual Super Slam for de Groot.
| Wheelchair women's singles | |
|---|---|
| 2021 Australian Open | |
| Champion |  Diede de Groot |
| Runner-up |  Yui Kamiji |
| Score | 6–3, 6–7(4–7), 7–6(10–4) |
| Draw | 8 |
| Seeds | 2 |
Seeds edit
Diede de Groot (champion)
Yui Kamiji (final)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Bracket edit
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 3 | 6 | ||||||||||||||||
| Aniek van Koot
| 0 | 6 | 4 | |||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| Momoko Ohtani
| 2 | 4 | ||||||||||||||||||
| Momoko Ohtani
| 6 | 6 | ||||||||||||||||||
 Lucy Shuker
| 2 | 2 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 64 | 710 | ||||||||||||||||
| 2 | Yui Kamiji
| 3 | 77 | 64 | ||||||||||||||||
 Angélica Bernal
| 1 | 2 | ||||||||||||||||||
 Kgothatso Montjane
| 6 | 6 | ||||||||||||||||||
| Kgothatso Montjane
| 1 | 7 | 0 | |||||||||||||||||
| 2 | Yui Kamiji
| 6 | 5 | 6 | ||||||||||||||||
 Macarena Cabrillana
| 0 | 1 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 6 | |||||||||||||||||
