USS San Pablo may refer to:
Ships edit
- USS San Pablo (AVP-30), a United States Navy ship in commission as a seaplane tender from 1943 to 1947 and as a hydrographic survey ship from 1948 to 1969
Literature and film edit
- USS San Pablo, a fictional United States Navy gunboat that is the setting for the 1962 novel The Sand Pebbles and the 1966 movie The Sand Pebbles