U49 may refer to:
- German submarine U-49, various vessels
- HMS Pheasant (U49), a sloop of the Royal Navy
- Small icosihemidodecahedron
- Small nucleolar RNA SNORD49
- Uppland Runic Inscription 49
- U49, a line of the Dortmund Stadtbahn
This disambiguation page lists articles associated with the title U49.
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