James Thayer may refer to:
- James Thayer (author) (born 1949), American author
- James Thayer (Medal of Honor) (1853–1886), United States Navy sailor and Medal of Honor recipient
- James Bradley Thayer (1831–1902), American legal writer and scholar
- James B. Thayer (1922–2018), brigadier general in the U.S. Army
This disambiguation page lists articles about people with the same name.
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