Sergio Santos may refer to:
- Sergio Santos (baseball) (born 1983), American baseball player
- Sérgio Santos (volleyball) (born 1975), also known as Serginho or Escadinha, Brazilian volleyball player
- Sergio Santos (footballer, born 1994), Brazilian football forward for FC Cincinnati
- Sérgio Santos (footballer, born 1998), Portuguese football forward for Portimonense
- Sergio Santos (footballer, born 2001), Spanish football right-back for Real Madrid
See also edit
- Sergio Dos Santos (born 1950), South African soccer player
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