Frank O'Donnell may refer to:
- Frank O'Donnell (footballer) (1911–1952), Scottish professional footballer
- Frank O'Donnell (actor) (1907–1956), Australian actor
- Frank A. O'Donnel (1852–1906), New York politician
- Frank Hugh O'Donnell (1846–1916), Irish nationalist writer and politician
- Frank J. Hugh O'Donnell (1894–1976), Irish critic, playwright and politician
- Francis Martin O'Donnell (born 1954), Irish and international diplomat, Ambassador of the Sovereign Order of Malta to Slovakia and retired former UN Resident Coordinator
This disambiguation page lists articles about people with the same name.
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