Open main menu

Mycobacterial porin

  (Redirected from MspA porin)

MspA porin is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eight-fold rotation symmetry that resembles a goblet and contains a central channel. Each protein subunit contains a beta-sandwich of immunoglobulin-like topology and a beta-ribbon arm that forms an oligomeric transmembrane beta-barrel.[1]

MspA
1uun opm.png
Identifiers
SymbolMspA
PfamPF09203
InterProIPR015286
SCOPe1uun / SUPFAM
TCDB1.B.24
OPM superfamily268
OPM protein1uun

ReferencesEdit

  1. ^ Schulz GE, Faller M, Niederweis M (2004). "The structure of a mycobacterial outer-membrane channel". Science. 303 (5661): 1189–92. doi:10.1126/science.1094114. PMID 14976314.