Luke Thompson may refer to:
- Sir Luke Thompson (politician) (1867–1941), British coal merchant and Conservative politician
- Luke Thompson (rugby league) (born 1995), English rugby league player for St Helens RLFC
- Luke Thompson (rugby union) (born 1981), Japanese rugby union player
- Luke Thompson (actor) (born 1988), British actor
- Luke Thompson (Australian footballer) (born 1991), Australian rules footballer
- Luke Willis Thompson (born 1988), New Zealand artist
This disambiguation page lists articles about people with the same name.
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