Long Island serial killer may refer to:
- Gilgo Beach serial killings, a series of murders between 1996 and 2011 in which the remains of 11 people were found on the South Shore of Long Island, New York
- Joel Rifkin (born 1959), an American serial killer sentenced for the murders of nine women between 1989 and 1993
- Robert Shulman, a serial killer who murdered five women between 1991 and 1996
- Richard Angelo, a serial killer who murdered at least four patients in 1987
- Richard Cottingham, a serial killer who murdered at least 18 women, four on Long Island
- Raymond Fernandez and Martha Beck, a serial killer couple who murdered a woman on Long Island in 1949