Juan de Zúñiga y Avellaneda, 1st Duke of Peñaranda de Duero (1551 – 4 September 1608) was a Spanish nobleman during the reigns of Philip II and Philip III.

Drawing of the 1st Duke of Peñaranda de Duero

He was a Knight of the Military Order of Santiago, the 6th consort count, iure uxoris, of Miranda del Castañar, a title awarded by king Henry IV of Castile on 9 February 1457 and the 1st Duke of Peñaranda, a title awarded by king Philip III on 22 May 1608.

In 1583, under King Philip II, he succeeded Carlo d'Aragona Tagliavia as Viceroy of Catalonia, a position he held until 1586 when he was succeeded by Manrique de Lara y Girón. In 1586, Juan de Zúñiga succeeded Pedro Girón, 1st Duke of Osuna to become the Viceroy of Naples and was succeeded by Enrique de Guzmán, 2nd Count of Olivares in 1595.

He served as President of the Council of Italy and, in 1600–1606, as the President of the Council of Castile, by then at the service of king Philip III of Spain.

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Government offices
Preceded by Viceroy of Catalonia
1583–1585
Succeeded by
Preceded by Viceroy of Naples
1586–1595
Succeeded by
Spanish nobility
Preceded by
New creation
Duke of Peñaranda de Duero
1608
Succeeded by
Diego de Zúñiga y Pacheco