José Serrano may refer to:
- José António Serrano (1851–1904), Portuguese physician and anatomist
- José E. Serrano (born 1943), Member of the U.S. House of Representatives for a portion of The Bronx, New York
- José M. Serrano (born 1972), his son, New York State Senator
- José Serrano (Ecuadorian politician) (born 1970), Ecuadorian political figure, currently Minister of the Interior
- José Serrano (composer) (1873–1941), Spanish zarzuela composer
- José María Galante Serrano (1948–2020), Spanish activist known as Chato Galante
- José Mariano Serrano (1788–1852), Bolivian member of the Congress of Tucumán
- José Serrano (footballer, born 1981), Spanish footballer
- Rosso José Serrano (born 1942), Colombian police officer
- José Serrano (footballer, born 2002), Venezuelan footballer
This disambiguation page lists articles about people with the same name.
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