Interstate 685 may refer to:
- Interstate 685 (Alabama), a planned future designation for a current stretch of I-85 in Montgomery, Alabama
- Interstate 685 (North Carolina), a planned future Interstate Highway following US 421 between I-40 in Greensboro, North Carolina, and I-95 near Fayetteville, North Carolina
- Interstate 685 (South Carolina), a designation for I-85 Business once proposed by civic leaders in Spartanburg, South Carolina
This disambiguation page lists articles about roads and streets with the same name.
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