Henry Preston may refer to:
- Henry Preston (cricketer) (1883–1964), English cricketer
- Sir Henry Preston, 3rd Baronet (1851–1897), English soldier, magistrate and footballer
- Henry Preston (antiquary) (1852-1940), geologist, archaeologist and numismatist, founder of Grantham Museum
- Henry Preston (MP for Nottingham), 1414–1417, MP for Nottingham
- Henry Preston (died 1434), MP for City of York