File:Wild-type and mutant IDH1 structures.png

Wild-type_and_mutant_IDH1_structures.png (697 × 446 pixels, file size: 366 KB, MIME type: image/png)

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English: The molecular structure of the IDH1 enzyme. Depiction of the R132H mutation that is prevalent in gliomas shown in zoomed section. This mutation is a substitution of histidine for arginine at codon 132 in the active site of the enzyme. This research was originally published in Molecular & Cellular Proteomics. Morris et al. Computational Tools for the Interactive Exploration of Proteomic and Structural Data. Mol Cell Proteomics. 2010; 9:1703-1715. © the American Society for Biochemistry and Molecular Biology.
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Source John H. Morris et al. Mol Cell Proteomics 2010;9:1703-1715
Author John H. Morris et al.

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1 August 2010

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