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Summary
| Description |
English: Translation of nanos mRNA is controlled by Smaug protein in Drosophila melanogaster. (A) Smaug, in the absence of Oskar protein, will bind with Drosophila Cup protein which inhibits the translational initiation by binding with eIF4e. It recruits deadenylation complex CCR4-NOT and causes a reduction in Poly-A-tail; considerably reducing the half-life of nanos mRNA. (B) At the same time at the posterior end of blastoderm Oskar binds with Smaug which allows nanos mRNA translation and formation of Nanos protein gradient in Drosophila blastoderm. |
| Date | |
| Source | Own work |
| Author | Arunviswanathan91 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:27, 24 October 2017 | | 2,116 × 1,962 (488 KB) | Arunviswanathan91 | Cross-wiki upload from en.wikipedia.org |
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