File:The structure of the alpha2 hook of AMPK Fig4a.jpg

The_structure_of_the_alpha2_hook_of_AMPK_Fig4a.jpg(454 × 410 pixels, file size: 56 KB, MIME type: image/jpeg)

Summary

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English: "Ribbons representation of the overlap of the γ subunit and hook regions from full-length α2/activator complex (coloured in pink and orange) and from the ΔCBM AMPK complex (coloured in grey), showing the close structural similarity of the hook region for α1 and α2 over the five strictly conserved residues. The two exchangeable AMP moieties are shown in stick representation (from the full-length structure) but the non-exchangeable AMP has been removed for clarity." Figure 4a from B.Xiao et al. "Structural basis of AMPK regulation by small molecule activators" Nature Communications 4 doi:10.1038/ncomms4017 . Image and description copied under CC-BY 3.0 licence.
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Source http://www.nature.com/ncomms/2013/131219/ncomms4017/full/ncomms4017.html
Author Bing Xiao, Matthew J. Sanders, David Carmena, Nicola J. Bright, Lesley F. Haire, Elizabeth Underwood, Bhakti R. Patel, Richard B. Heath, Philip A. Walker, Stefan Hallen, Fabrizio Giordanetto, Stephen R. Martin, David Carling & Steven J. Gamblin

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19 December 2013

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current15:49, 14 November 2014Thumbnail for version as of 15:49, 14 November 2014454 × 410 (56 KB)MartinPoulterUser created page with UploadWizard
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