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The_effect_of_FTO_as_an_m6A_demethylase_in_ovarian_aging.png (635 × 423 pixels, file size: 257 KB, MIME type: image/png)
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Summary
| Description |
English: ROS accumulation during ovarian aging causes low expression of the demethylase FTO in GCs, and the resulting increase in m6A retards the FOS-mRNA degradation for upregulating FOS in GCs. Ultimately, the aging of GCs is promoted followed by the ovarian aging acceleration. |
| Date | |
| Source | The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging. https://doi.org/10.1038/s41419-021-04016-9 |
| Author | Jiang, Z. X., Wang, Y. N., Li, Z. Y., Dai, Z. H., He, Y., Chu, K., Gu, J. Y., Ji, Y. X., Sun, N. X., Yang, F., & Li, W. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 21:34, 15 June 2022 | | 635 × 423 (257 KB) | Idilertem | Uploaded a work by Jiang, Z. X., Wang, Y. N., Li, Z. Y., Dai, Z. H., He, Y., Chu, K., Gu, J. Y., Ji, Y. X., Sun, N. X., Yang, F., & Li, W. from The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging. https://doi.org/10.1038/s41419-021-04016-9 with UploadWizard |
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