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File:The basic unit of chromatin organization is the nucleosome, which comprises 147 bp of DNA wrapped ar.jpg

The_basic_unit_of_chromatin_organization_is_the_nucleosome,_which_comprises_147_bp_of_DNA_wrapped_ar.jpg ‎(600 × 529 pixels, file size: 126 KB, MIME type: image/jpeg)

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English: The basic unit of chromatin organization is the nucleosome, which comprises 147 bp of DNA wrapped around a core of histone proteins. Nucleosomes can be organized into higher order structures and the level of packaging can have profound consequences on all DNA-mediated processes including gene regulation. Euchromatin is associated with an open chromatin conformation and this structure is permissible for transcription whereas heterochromatin is more compact and refractory to factors that need to gain access to the DNA template. Nucleosome positioning and chromatin compaction can be influenced by a wide-range of processes including modification to both histones and DNA.
Date Published May 31, 2009.
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[1] Direct
StemBook Figure 1 The basic unit of chromatin organization is the nucleosome, which comprises 147 bp of DNA wrapped ar

  • Sha, K. and Boyer, L. A. The chromatin signature of pluripotent cells (May 31, 2009), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.45.1, http://www.stembook.org.
Author Sha, K. and Boyer, L. A. The chromatin signature of pluripotent cells (May 31, 2009), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.45.1, http://www.stembook.org.
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