File:Simplified overview of the biosynthesis and catabolism of serotonin and the catecholamines TH circled in red.jpg

Summary

Description
English: Simplified overview of the biosynthesis and catabolism of serotonin and the catecholamines, with TH circled in red. Note that different parts of these processes take place in different tissues (see text for details). Abbreviations: 3-MT, 3-methoxytyramine; 5-HTP, 5-hydroxytryptophan; 5HIAA, 5-hydroxyindolacetic acid; AAAHs, aromatic amino acid hydroxylases; AAAs, aromatic amino acids; AADC, aromatic acid decarboxylase; BH4, (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin; COMT, catechol-O-methyltransferase; DBH, dopamine beta-hydroxylase; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; L-DOPA, L-3,4-dihydroxyphenylalanine; MN, metanephrine; MAO, monoamine oxidase; MPHG, 3-methoxy-4-hydroxyphenylethylene glycol; NMN, normetanephrine; PAH, phenylalanine hydroxylase; PLP, pyridoxal phosphate; PNMT, phenylethanolamine N-methyltransferase; TH, tyrosine hydroxylase; TPH, tryptophan hydroxylase.
Date
Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625014/
Author Gyrid Nygaard et al., 2021

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Simplified overview of the biosynthesis and catabolism of serotonin and the catecholamines, with TH circled in red

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12 November 2021

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