File:Sickle Cell Anemia and its Protection Against Malaria.svg

Original file(SVG file, nominally 512 × 311 pixels, file size: 159 KB)

Summary

Description
English: In series A the red blood cell becomes sickled after interaction with the malarial merozoite, which then begins to multiply in the cell (schizont). Due to the heterozygous nature of the cell, and the hemoglobin inside it causing sickling, likely as a result of the lowering of the pH and deoxygenation, the cell can be targeted and eliminated by macrophages before the infection can reproduce, lowering the overall amount of infected cells in comparison to normal red blood cells. In series B the normal red blood cell becomes infected by the merozoite, which multiplies inside the cell, eventually causing hemolysis of the cell, and the offspring go on to infect other cells.
Date
Source Own work
Author Dsheffer02

Licensing

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.

Captions

Possible advantage of being heterozygous for sickle cell anemia disease (A) vs. normal blood cell response (B) when infected with malaria.

Items portrayed in this file

depicts

12 June 2019

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current14:10, 12 June 2019Thumbnail for version as of 14:10, 12 June 2019512 × 311 (159 KB)Dsheffer02User created page with UploadWizard
The following pages on the English Wikipedia use this file (pages on other projects are not listed):

Global file usage

The following other wikis use this file:

Metadata