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Summary
| Description |
English: Peroxisomal protein targeting to the matrix. (1) PTS1 sequence in a cytosolic protein binds to PEX5. (2) PEX5 with bound protein forms a complex with peroxisome membrane protein PEX14, releasing the protein into the matrix (3). The unbound PEX5 complexed with PEX14 becomes ubiquitinylated by PEX2/PEX12/PEX10 membrane complex (4). Followed by ATP dependent removal of PEX5 via cytosolic PEX1/PEX6 complex. The cycle is free to continue in importing proteins targeted to the peroxisomal matrix. |
| Date | |
| Source | Own work |
| Author | Neeko Sneako2 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 03:15, 1 October 2022 | | 801 × 472 (57 KB) | Neeko Sneako2 | Uploaded own work with UploadWizard |
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