E99 can refer to:
- King's Indian Defense, Encyclopaedia of Chess Openings code
- E 99 road (United Arab Emirates), a road in the United Arab Emirates
- Embraer R-99, an aircraft type
- European route E99, European road in Turkey
- Element 99, a fictional element in the video game Singularity.
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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