Galactitol

Galactitol
Names
	IUPAC name D-Galactitol
	Systematic IUPAC name (2R,3S,4R,5S)-hexane-1,2,3,4,5,6-hexol
	Other names Dulcitol
Identifiers
CAS Number	608-66-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16813 ;
ChEMBL	ChEMBL1773904 ;
ChemSpider	11357 ;
ECHA InfoCard	100.009.242
PubChem CID	11850;
UNII	113ZQ1Y7DD ;
CompTox Dashboard (EPA)	DTXSID1046051 ;
	InChI InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6- Key: FBPFZTCFMRRESA-GUCUJZIJSA-N ; InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6- Key: FBPFZTCFMRRESA-GUCUJZIJBM;
	SMILES O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)CO;
Properties
Chemical formula	C6H14O6
Molar mass	182.172 g/mol
Magnetic susceptibility (χ)	-112.40·10−6 cm3/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose.^[1] It has a slightly sweet taste.^[1] In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts.^[2]

Galactitol is produced from galactose in a reaction catalyzed by aldose reductase.

The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase, an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. This disorder leads to cataracts caused by galactitol buildup.

References

^ ^a ^b "Galactitol - Compound Summary". National Center for Biotechnology Information. Retrieved 2008-08-06.
^ Roth, KS (September 10, 2007). "Galactokinase Deficiency". eMedicine. WebMD. Retrieved 2008-08-08.

External links

Media related to Galactitol at Wikimedia Commons

[pubchem-1] "Galactitol - Compound Summary". National Center for Biotechnology Information. Retrieved 2008-08-06.

[eMedicine-2] Roth, KS (September 10, 2007). "Galactokinase Deficiency". eMedicine. WebMD. Retrieved 2008-08-08.

[1]

[2]