Esproquin is an α2-adrenergic receptor agonist derived from tetrahydroisoquinoline.[1] It has a positive inotropic effect, suggesting potential use in treatment of chronic heart failure.[2]
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Other names | Esproquine |
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Formula | C14H21NOS |
Molar mass | 251.39 g·mol−1 |
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References
edit- ^ Gray AP, Shiley RH (July 1973). "Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives". Journal of Medicinal Chemistry. 16 (7): 859–61. doi:10.1021/jm00265a028. PMID 4146907.
- ^ Kotelanski B, Grozmann RJ, Cohn JN (1973). "Positive inotropic effect of oral esproquin in normal subjects". Clinical Pharmacology and Therapeutics. 14 (3): 427–33. doi:10.1002/cpt1973143427. PMID 4698571. S2CID 46266823.