Elaine Wyllie (born August 26, 1953) is a professor emeritus of neurology at the Cleveland Clinic Lerner College of Medicine and emeritus staff physician in Cleveland Clinic's Epilepsy Center. Her research focused on the role of epilepsy surgery in children with drug-resistant seizures.[3]: 991–993  [4]

Elaine Wyllie
Headshot of Elaine Wyllie
Wyllie in 2019
Born (1953-08-26) August 26, 1953 (age 71)
EducationShimer College (BA), Indiana University School of Medicine (MD)
Years active1978 to present
Known forEpilepsy surgery in children
Medical career
ProfessionPediatric Neurologist
InstitutionsCleveland Clinic, Cleveland, Ohio, 1985 to 2023[1]
Sub-specialtiesEpilepsy
ResearchList of all publications [2]
AwardsEpilepsy Research Award from the American Epilepsy Society (1994), Cleveland Clinic Master Clinician Award, Herbert H. Jasper Award from the American Clinical Neurophysiology Society (2021), J. Kiffin Penry Award for Excellence in Epilepsy Care from the American Epilepsy Society (2022)

In 2021, her clinical work was highlighted in a commemorative video [5] for the 100th anniversary of Cleveland Clinic.

Education and training

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Wyllie graduated from Indiana University School of Medicine in 1978. She trained in pediatrics at Riley Children's Hospital and Rainbow Babies and Children's Hospital, and in pediatric neurology, epilepsy, clinical neurophysiology, and sleep medicine at Cleveland Clinic.

Career and contributions

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In 1985, Wyllie joined the staff of Cleveland Clinic's neurology department. In 1988 she organized the first Cleveland Clinic International Epilepsy Symposium, focused on pediatric epilepsy.[6]

In the 1990s, together with her colleagues, Wyllie helped to establish a distinct program for delivery of epilepsy care to pediatric patients in the Cleveland Clinic Epilepsy Center. She also worked on the national level to focus attention on pediatric epilepsy education and research, serving on many committees within the American Epilepsy Society and other medical organizations.[3]

Wyllie's research has focused on surgical intervention for children with uncontrolled seizures to improve quality of life and maximize developmental potential.[7] [8] [9] Her work helped broaden the selection criteria for surgery to include children with non-localized EEG patterns when an early developmental brain abnormality is present, [10] and children with MRI abnormalities in both brain hemispheres when seizures arise from just one side.[11] These concepts have been adopted at epilepsy centers worldwide.[12] [13] [14]

Wyllie is the editor of Wyllie's Treatment of Epilepsy, now in its seventh edition.[15] She authored Cleveland Clinic Guide to Epilepsy,[16] a book for families experiencing epilepsy. Wyllie has also published and presented her research widely in hundreds of articles and presentations.[3]

Awards and honors

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  • Epilepsy Research Award from the American Epilepsy Society, 1994[17]
  • Cleveland Clinic Master Clinician Award[4]
  • Herbert H. Jasper Award from the American Clinical Neurophysiology Society, 2021[18]
  • J. Kiffin Penry Award for Excellence in Epilepsy Care from the American Epilepsy Society, 2022[17]

Personal life

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Together with her husband, Robert Wyllie (married 1979), Wyllie has two sons. Her hobby is dance, including ballroom, jazz, and tango. [19] [20]

References

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  1. ^ "Cleveland Clinic Alumni Connection (vol. 34, issue 1, 2024, pg. 8)".
  2. ^ "Google Scholar: Elaine Wyllie".
  3. ^ a b c Ashwal, Stephen (2021). Child Neurology: Its Origins, Founders, Growth, and Evolution (2nd ed.). Cambridge, MA: Elsevier, Academic Press. ISBN 978-0128216354.
  4. ^ a b "J. Kiffin Penry Award for Excellence in Epilepsy Care from the American Epilepsy Society (2022)".
  5. ^ "A Culture of Breakthroughs".
  6. ^ "Proceedings of the 1988 Cleveland Clinic International Epilepsy Symposium". Cleve Clin J Med. 56 (Suppl Part 1): S1:157. 1989.
  7. ^ Wyllie, Elaine; Chee, Michael; Granstrom, Marja-Liisa; DelGiudice, Ennio; Estes, Melinda; Comair, Youssef; Pizzi, Margaret; Kotagal, Prakash; Bourgeois, Blaise; Lüders, Hans (1993). "Temporal lobe epilepsy in early childhood". Epilepsia. 34 (5): 859–68. doi:10.1111/j.1528-1157.1993.tb02103.x. PMID 8404738. S2CID 32505052.
  8. ^ Wyllie, Elaine; Comair, Youssef G.; Kotagal, Prakash; Raja, Shanker; Ruggieri, Paul (1996). "Epilepsy surgery in infants". Epilepsia. 37 (7): 625–37. doi:10.1111/j.1528-1157.1996.tb00626.x. PMID 8681894. S2CID 21169672.
  9. ^ Wyllie, Elaine; Comair, Youssef G.; Kotagal, Prakash; Bulacio, Juan; Bingaman, William; Ruggieri, Paul (1998). "Seizure outcome after epilepsy surgery in children and adolescents". Ann Neurol. 44 (5): 740–8. doi:10.1002/ana.410440507. PMID 9818929. S2CID 9509230.
  10. ^ Wyllie, Elaine; Lachhwani, Deepak K.; Gupta, Ajay; Chirla, Adina; Cosmo, Gary; Worley, Sarah; Kotagal, Parkash; Ruggieri, Paul; Bingaman, William (2007). "Successful surgery for epilepsy due to early brain lesions despite generalized EEG findings". Neurology. 69 (4): 389–97. doi:10.1212/01.wnl.0000266386.55715.3f. PMID 17646632. S2CID 7113539.
  11. ^ Hallbook, Tove; Ruggieri, Paul; Chirla, Adina; Lachhwani, Deepak K.; Gupta, Ajay; Kotagal, Prakash; Bingaman, William E.; Wyllie, Elaine (2010). "Contralateral MRI abnormalities in candidates for hemispherectomy for refractory epilepsy". Epilepsia. 51 (4): 556–63. doi:10.1111/j.1528-1167.2009.02335.x. PMID 19817811. S2CID 26702537.
  12. ^ YJ, Lee; HC, Kang; JS, Lee; SH, Kim; DS, Kim; KW, Shim; YH, Lee; TS, Kim; HD, Kim (2010). "Resective pediatric epilepsy surgery in Lennox-Gastaut syndrome". Pediatrics. 125 (1): 58–66. doi:10.1542/peds.2009-0566. PMID 20008422. S2CID 4836738.
  13. ^ JW, Kang; S, Eom; W, Hong; HE, Kwon; S, Park; A, Ko; HC, Kang; JS, Lee; YM, Lee; DS, Kim; HD, Kim (2018). "Long-term Outcome of Resective Epilepsy Surgery in Patients With Lennox-Gastaut Syndrome". Pediatrics. 142 (4): e20180449. doi:10.1542/peds.2018-0449. PMID 30194277. S2CID 52172887.
  14. ^ Keator, Cynthia G. (2021). "Epilepsy Surgery is a Viable Treatment for Lennox Gastaut Syndrome". Semin Pediatr Neurol. 38 (July): 100894. doi:10.1016/j.spen.2021.100894. PMID 34183143. S2CID 235673411.
  15. ^ Wyllie Ed., Elaine (2020). Wyllie's Treatment of Epilepsy: Principles and Practice. 7. Wolters Kluwer. ISBN 9781496397690.
  16. ^ Wyllie Ed., Elaine (2016). Cleveland Clinic Guide to Epilepsy: Essential Reading for Families. 3. ISBN 978-0692737682.
  17. ^ a b "American Epilepsy Society Past Awardees".
  18. ^ "Herbert H. Jasper Awardees".
  19. ^ "Tango Wyllie". 7 August 2022.
  20. ^ "Inspirations and Insights from Cleveland Clinic Women Docs".