Diversity arrays technology

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Diversity arrays technology (DArT) is the name of a technology used in molecular genetics to develop sequence markers for genotyping and other techniques for genetic analysis.

DArT is based on microarray hybridizations that detect the presence versus absence of individual fragments in genomic representations. DArT relies on the screening of a randomized library of fragments to improve the chances at detection.[1] The technology has significant advantages over other array based Single-nucleotide polymorphism detection technologies in the analysis of polyploid plants.[2]

ReferencesEdit

  1. ^ Jaccoud D, Peng K, Feinstein D, Kilian A (February 2001). "Diversity arrays: a solid state technology for sequence information independent genotyping". Nucleic Acids Res. 29 (4): 25e–25. doi:10.1093/nar/29.4.e25. PMC 29632. PMID 11160945.
  2. ^ Wenzl P, Carling J, Kudrna D, et al. (June 2004). "Diversity Arrays Technology (DArT) for whole-genome profiling of barley". Proc. Natl. Acad. Sci. U.S.A. 101 (26): 9915–20. Bibcode:2004PNAS..101.9915W. doi:10.1073/pnas.0401076101. PMC 470773. PMID 15192146.