Tritoqualine

(Redirected from C26H32N2O8)

Tritoqualine, also known as hypostamine, is an inhibitor of the enzyme histidine decarboxylase and therefore an atypical antihistamine, used for the treatment of urticaria and allergic rhinitis[1] with no known adverse effects.[citation needed]

Tritoqualine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 7-amino-4,5,6-triethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H32N2O8
Molar mass500.548 g·mol−1
3D model (JSmol)
  • CCOC1=C(C(=C(C2=C1C(OC2=O)C3C4=C(C5=C(C=C4CCN3C)OCO5)OC)N)OCC)OCC

References

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  1. ^ Pradalier A, Hentschel V, Prouzeau S, Legallais D, Lefrancois G (April 2003). "Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis". Revue Française d'Allergologie et d'Immunologie Clinique. 43 (3): 175–9. doi:10.1016/S0335-7457(03)00047-9.