Biconcave disc

(Redirected from Biconcave disk)

In geometry and mathematical biology, a biconcave disc — also referred to as a discocyte[1] — is a geometric shape resembling an oblate spheroid with two concavities on the top and on the bottom.

A biconcave disc

Biconcave discs appear in the study of cell biology, as an approximation to the shape of certain cells, including red blood cells.

Mathematical model edit

A biconcave disc can be described mathematically by

 

where z(r) is the height of the surface as a function of radius r, D is the diameter of the disc, and a0, a1, a2 are coefficients describing the shape. The above model describes a smooth surface; actual cells can be much more irregular.

Biology edit

Erythrocytes are in the shape of a biconcave disc. An erythrocyte is also known as a red blood cell and transports oxygen to and from tissues.[1][2]

References edit

  1. ^ a b Kuchel, Philip W.; Fackerell, Edward D. (1999). "Parametric-equation representation of biconcave erythrocytes". Bulletin of Mathematical Biology. 61 (2): 209–220. doi:10.1006/bulm.1998.0064. ISSN 1522-9602. PMID 17883208. S2CID 39585695.
  2. ^ Muñoz, Sagrario; Sebastián, José L.; Sancho, Miguel F.; Álvarez, Gabriel (2014-03-01). "Elastic energy of the discocyte–stomatocyte transformation". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1838 (3): 950–956. doi:10.1016/j.bbamem.2013.10.020. ISSN 0005-2736. PMID 24192054.