Andre Smith may refer to:
Sports edit
American football edit
- Andre Smith (offensive tackle) (born 1987), American football offensive tackle
- Andre Smith (tight end) (born 1988), American football tight end
- Andre Smith (linebacker) (born 1997), American football linebacker
Basketball edit
- Andre Smith (basketball, born 1958), American college basketball player for the Nebraska Cornhuskers
- Andre Smith (basketball, born 1985), American expatriate professional basketball
Others edit
- J. Andre Smith (1880–1959), American war artist