Al-Uthmaniyya Madrasa (al-Madrasa al-ʿUthmāniyya) can refer to:
- Al-Uthmaniyya Madrasa (Jerusalem)
- Al-Uthmaniyya Madrasa (Aleppo)
- Madrasa al-'Uthmaniyya (later the Madrasa al-Kamiliyya) in Hayy Buzuriyya, Damascus.
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