Statherin is a protein in humans that is encoded by the STATH gene.[3][4] It prevents the precipitation of calcium phosphate in saliva, maintaining a high calcium level in saliva available for remineralisation of tooth enamel and high phosphate levels for buffering.[5]

STATH
Identifiers
AliasesSTATH, STR, statherin
External IDsOMIM: 184470; HomoloGene: 88673; GeneCards: STATH; OMA:STATH - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003154
NM_001009181

n/a

RefSeq (protein)

NP_001009181
NP_003145

n/a

Location (UCSC)Chr 4: 70 – 70 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

References

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  1. ^ a b c ENSG00000126549 GRCh38: Ensembl release 89: ENSG00000282891, ENSG00000126549Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Sabatini LM, Carlock LR, Johnson GW, Azen EA (Jan 1988). "cDNA cloning and chromosomal localization (4q11-13) of a gene for statherin, a regulator of calcium in saliva". Am J Hum Genet. 41 (6): 1048–60. PMC 1684366. PMID 3502720.
  4. ^ "Entrez Gene: STATH statherin".
  5. ^ Hay DI, Smith DJ, Schluckebier SK, Moreno EC (1984). "Relationship between concentration of human salivary statherin and inhibition of calcium phosphate precipitation in stimulated human parotid saliva". J. Dent. Res. 63 (6): 857–63. doi:10.1177/00220345840630060901. PMID 6429216. S2CID 72916849.

Further reading

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