The human AMY1C gene encodes the protein Amylase, alpha 1C (salivary). [3]

AMY1C
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesAMY1C, AMY1, amylase, alpha 1C (salivary), amylase alpha 1C (salivary), amylase alpha 1C
External IDsOMIM: 104702; HomoloGene: 133998; GeneCards: AMY1C; OMA:AMY1C - orthologs
EC number3.2.1.1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008219
NM_001346780

n/a

RefSeq (protein)

NP_001008220
NP_001333709
NP_001008222
NP_004029
NP_001008219

n/a

Location (UCSC)Chr 1: 103.75 – 103.76 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either the salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland.[4] See also Amylase § Evolution.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187733Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: Amylase, alpha 1C (salivary)". Retrieved 2013-02-14.
  4. ^ [provided by RefSeq, Jul 2008]. ##RefSeq-Attributes-START## Transcript_exon_combination_evidence :: AK313275.1 [ECO:0000332] ##RefSeq-Attributes-END##
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  • Overview of all the structural information available in the PDB for UniProt: P04745 (Human Alpha-amylase 1) at the PDBe-KB.

Further reading

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