Karl Klein may refer to:
- Karl Klein (priest) (1769-1824), German priest and publicist
- Karl Klein (historian) (1806-1870), German historian and writer
- Karl Klein (bishop) (1819-1898), German clergyman, Bishop of Limburg
- Karl Klein (writer) (1838-1898), Alsatian theologian and writer
- Karl Klein (1873-1934), German architect and first state conservator of the Saar region, see Carl Klein (architect)
- Karl Klein (party functionary) (1886-1960), German party functionary and trade union official
- Karl Klein (painter) (1898-1943), painter in Paris
- Karl Klein (murderer) (1901-1993), German politician and suspected police murderer
- Karl Klein (lawyer) (1904-1976), federal judge
- Karl Klein (theologian) (1912-2009), German theologian
- Karl Klein (trade unionist) (1949-2007), Austrian trade union official
- Karl Klein (politician) (born 1956), German politician, MdL Baden-Württemberg
- Karl Klein (footballer) (born 1960), German footballer
- Karl August von Klein (also Carl August von Klein; 1794-1870), German composer, painter and writer
- Karl Christian Klein (also Carl Christian Klein; 1772-1825), German surgeon and author
- Karl Egon Klein (1926-2018), German physician
- Karl Frank Klein (1922-2006), Canadian politician and farmer
This disambiguation page lists articles associated with the title Karl Klein.
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