ZDHHC17

Zinc finger, DHHC-type containing 17
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ZDHHC17; HIP14; HIP3; HYPH
External IDs OMIM607799 MGI2445110 HomoloGene56324 GeneCards: ZDHHC17 Gene
RNA expression pattern
PBB GE ZDHHC17 217486 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23390 320150
Ensembl ENSG00000186908 ENSMUSG00000035798
UniProt Q8IUH5 Q80TN5
RefSeq (mRNA) NM_015336 NM_172554
RefSeq (protein) NP_056151 NP_766142
Location (UCSC) Chr 12:
77.16 – 77.25 Mb
Chr 10:
110.94 – 111.01 Mb
PubMed search [1] [2]

Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene.[1][2][3]


Interactions

ZDHHC17 has been shown to interact with Huntingtin.[4][5]

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References

  1. ^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Oct 1998). "Huntingtin interacts with a family of WW domain proteins". Hum Mol Genet 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202. 
  2. ^ Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport". J Biol Chem 283 (48): 33365–74. doi:10.1074/jbc.M801469200. PMC 2662264. PMID 18794299. 
  3. ^ "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17". 
  4. ^ Faber, P W; Barnes G T, Srinidhi J, Chen J, Gusella J F, MacDonald M E (Sep. 1998). "Huntingtin interacts with a family of WW domain proteins". Hum. Mol. Genet. (ENGLAND) 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. ISSN 0964-6906. PMID 9700202. 
  5. ^ Singaraja, Roshni R; Hadano Shinji, Metzler Martina, Givan Scott, Wellington Cheryl L, Warby Simon, Yanai Anat, Gutekunst Claire-Anne, Leavitt Blair R, Yi Hong, Fichter Keith, Gan Lu, McCutcheon Krista, Chopra Vikramjit, Michel Jennifer, Hersch Steven M, Ikeda Joh-E, Hayden Michael R (Nov. 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis". Hum. Mol. Genet. (England) 11 (23): 2815–28. doi:10.1093/hmg/11.23.2815. ISSN 0964-6906. PMID 12393793. 
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Further reading



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Last modified on 17 March 2013, at 02:49