User talk:WikiDan61/LATE

Is this getting there...?

Glad to edit however you'd like. The reason I put all the new headings and whatnot is that these are what the Wikipedia formatting outline is supposed to look like..?

Thanks,

Pete Nelson Pete Nelson from UKY (talk) 14:06, 13 June 2024 (UTC)

Are we getting to where we can swop in the new LATE entry?

thanks! 128.163.238.24 (talk) 21:03, 27 June 2024 (UTC)

@Pete Nelson from UKY: The first comment I'd make is that the extensive use of bullet lists reduces the readability of the article. This is a great way to create an outline, but Wikipedia articles want to be more prose-like. As an example, I'd take this section:

* Memory Impairment: The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory ^[1]. This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently.

• “Pure LATE”: gradual Cognitive Decline: The amnestic syndrome in LATE tends to worsen gradually, leading to significant memory deficits over time.  Unlike more rapidly progressive dementias, the cognitive decline in LATE, when it is the chief pathology present is typically slow.
• The common scenario where LATE is combined with Alzheimer’s disease: a more swift and severe cognitive impairment and dementia.  Approximately ½ of dementia in advanced age includes both Alzheimer’s disease and LATE pathologies, and these individuals are at risk for more swift and severe disease course ^[2].
• Dementia: This is a clinical syndrome, rather than a particular disease process – it can be caused by many different subtypes of brain disease, which often occur in combination with each other.  Thus, many different diseases including LATE contribute to dementia.  The implications of the term “dementia” are that there is cognitive impairment severe enough to impair activities of daily living such as feeding oneself.

and rewrite as:

The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory.^[1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. The amnestic syndrome in LATE tends to worsen gradually, leading to significant memory deficits over time.  Unlike more rapidly progressive dementias, the cognitive decline in LATE, when it is the chief pathology present is typically slow.

The term dementia refers to a clinical syndrome, rather than a particular disease process – it can be caused by many different subtypes of brain disease, which often occur in combination with each other.  Thus, many different diseases including LATE contribute to dementia. The implications of the term dementia are that there is cognitive impairment severe enough to impair activities of daily living such as feeding oneself. Approximately half of dementia in advanced age includes both Alzheimer’s disease and LATE pathologies, and these individuals are at risk for more swift and severe disease course.^[2]

Note here that I've replaced your valid citations with pseudo-citations so as not to have them cluttering this talk page. The entire article can benefit from this type of editing. WikiDan61^ChatMe!_ReadMe!! 15:27, 13 June 2024 (UTC)

I made some more edits, removed bullets and made the text more prose-like. Better? Pete Nelson from UKY (talk) 16:32, 13 June 2024 (UTC)

@Pete Nelson from UKY: Getting there. I've taken further steps: removing extraneous subheadings and odd indentations. I think there's still some redundancy to be addressed. As a specific example, you have a section on "Impact on patients" and a separate section on "Quality of life considerations". These seem like they are basically discussing the same issue and should be combined. There are also still some statements (and whole sections) that have no citations; that should be addressed. WikiDan61^ChatMe!_ReadMe!! 17:01, 13 June 2024 (UTC)

Thanks for all the help Dan61!

I made suggested changes, I'm grateful for your complementary work.

LMK if more is needed,

Pete Pete Nelson from UKY (talk) 17:36, 13 June 2024 (UTC)

Hi WikiDan, not sure if you're around but I'd be glad to make more changes if you'd like to the LATE site. Otherwise, could it be swopped in?

Thanks!

Pete Nelson, U. Kentucky Pete Nelson from UKY (talk) 14:51, 17 June 2024 (UTC)

Can we make the switch-in to swop out the prior page for this one?

Thanks,

Pete Pete Nelson from UKY (talk) 20:25, 24 June 2024 (UTC)

@Pete Nelson from UKY: Sorry for the delay -- sometimes life gets in the way. I think you've done some great work with this article, but I'm not an expert in the subject matter. I'd like to ask someone from WP:WikiProject Medicine to take a look. WikiDan61^ChatMe!_ReadMe!! 21:38, 27 June 2024 (UTC)

Sounds great! Thanks a ton.

Sincerely,

Pete N Pete Nelson from UKY (talk) 21:52, 27 June 2024 (UTC)