User talk:Dssalven/sandbox
Latest comment: 5 years ago by HeatherKJ4
Heather's Peer Review
- Include an overview of the function in the article's Introduction.
- Re-order the Function subcategory so that it moves from more basic overall concepts to the more complex, technical concepts. It took me three read-throughs to understand that the enzyme functions as part of the cell cycle. Place that at the very beginning of the paragraph.
- This part of the Function subcategory, "The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, also known as Cdk1 in humans", doesn't seem to really talk about Function. Move it to a new subcategory.
- Mechanism of CDK2 Activation: change "This conformational change also relocates the activation loop to the C-lobe, revealing the ATP binding site now available for new interactions" to "This conformational change also relocates the activation loop to the C-lobe, revealing the ATP binding site and making it available for new interactions".
- Try to go through the whole thing and think of simpler sentence structures.
- Ex. Mechanism of CDK2 Activation: "It is unique in the way that it interacts with the respective cyclins over both lobes of the protein" can be -> "Its interaction with cyclins over both of its lobes is unique." (Although I don't understand the original sentence very well. The sentence before says that one cyclin protein binds at an active site between the N and C lobes, so shouldn't the next sentence say it binds between the lobes instead of over them?)
- Ex. CDK2-Cyclin E Complex and DNA Replication: "The success of the cell division process is dependent on the precise regulation of processes at both cellular and tissue levels" -> "Successful cell division depends on precise regulation of both cell and tissue processes."
- Try to simplify your language, i.e. "showed" instead of "demonstrated",
- Try to include as many links as possible on your technical terms, because you have a lot and it's easy to get lost.
- Almost every sentence here needs a citation. I'm pretty sure it's okay if it's to the same source.
HeatherKJ4 (talk) 19:26, 15 November 2018 (UTC)