 | |
 | |
| Clinical data | |
|---|---|
| Trade names | pHisoHex, Gamophen, Septisol, Turgex, Germa-Medica, others |
| AHFS/Drugs.com | Monograph |
| Drug class | Antiseptic[1] |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C13H6Cl6O2 |
| Molar mass | 406.89 g·mol−1 |
| 3D model (JSmol) | |
| Density | 1.71 g/cm3 |
| Melting point | 163 to 165 °C (325 to 329 °F) |
| Boiling point | 471 °C (880 °F) |
| |
| |
Hexachlorophene, also known as pHisoHex, is an antiseptic which was used by health care workers to clean their hands before surgery.[1] Before the 1970s it was also used to wash newborns.[2] It is applied to the skin.[1]
Common side effects include dermatitis, sunburn, and dry skin.[1] Other side effects may include neurotoxicity with seizures and potentially death.[1] Small amounts stop bacterial from growing; however exactly how this occurs is unclear.[1]
Hexachlorophene came into medical use in 1948.[3] In the United States a bottle of 150 mL of 3% solution was about 36 USD.[4] It has subsequently been discontinued in the United States and most other countries.[1][5]
References
edit- ^ a b c d e f g h "Hexachlorophene Monograph for Professionals". Drugs.com. Archived from the original on 5 September 2015. Retrieved 10 December 2021.
- ^ Martin, Richard J.; Fanaroff, Avroy A.; Walsh, Michele C. (4 October 2010). Fanaroff and Martin's Neonatal-Perinatal Medicine E-Book: Diseases of the Fetus and Infant. Elsevier Health Sciences. p. 828. ISBN 978-0-323-08111-5. Archived from the original on 11 December 2021. Retrieved 10 December 2021.
- ^ Pilapil, Virgilio R. (1 March 1966). "Hexachlorophene Toxicity in an Infant". Archives of Pediatrics & Adolescent Medicine. 111 (3): 333. doi:10.1001/archpedi.1966.02090060143023.
{{cite journal}}:|access-date=requires|url=(help) - ^ "PHisoHex Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 10 December 2021.
- ^ Mehlhorn, Heinz (2008). Encyclopedia of Parasitology: A-M. Springer Science & Business Media. p. 1442. ISBN 978-3-540-48994-8. Archived from the original on 2021-12-11. Retrieved 2021-12-10.