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Different Dosage advice, lack of citation edit
The dose section is contrary to what my Pediatrician just prescribed for my child's pinworm infection. We were prescribed 2 x 100mg tablets to be taken two weeks apart. This at least partially contradicts the dose section. It appears inaccurate and has no citations.
—Preceding unsigned comment added by 72.85.131.243 (talk) 02:46, 11 June 2009 (UTC)
I too had a different dosage... My doctors have given me 2x100 mg a day, for 3 days
70.164.194.201 (talk) 15:47, 24 August 2010 (UTC)
Mechanism of action is poorly written edit
Mebendazole blocks polymixin based microtubule formation, destroying the glucose uptake receptor in the nematode. This article is poorly written and incorrect.
What exactly is the mechanism of action of this drug, the article mentions both glucose uptake inhabition and preventing spindle formation, vastly different actions. Which is it? Both?
Onco_p53 00:00, 16 March 2006 (UTC)
Information from the manufacturers website edit
I agree that this is an incredibly badly written page. What does "selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell" mean? That the drug prevents the host's intestine from absorbing these nutrients? So it kills the patient?
The manufacturers website says that it prevents the worms taking up glucose and they die because of lack of energy.
Image filenames ends in .svg.png which trigger some email malware scanners edit
Image filenames ends in .svg.png which, when the content is emailed, is identified as an attempt to hide the file ending by some email malware scanners. Please re-name all the image files, removing the .svg parts! --Leif Erlingsson (talk) 15:45, 16 October 2012 (UTC)
CAS registry have no information about history of discovery of this medicine edit
The main links, like CAS registry, have no information about history of discover and/or massive use. PS: the "Date of Entry" (1974) of CAS is not the "entry year". --Krauss (talk) 19:05, 29 December 2013 (UTC)
Cost in Brazil edit
In Brazil 400 mg Albendazole costs about US$2.00.
— Preceding unsigned comment added by 177.105.203.119 (talk) 00:10, 24 January 2017 (UTC)
Inconsistent single dose cost in the USA edit
Which is it? Currently the article claims both:
“In the United States a single dose is about 18 USD.[3]”
“In the United States a single dose is about 440.00 USD as of 2016, while in Australia and the UK it costs about 5 USD.[8]”
— Preceding unsigned comment added by Polarbear ed (talk • contribs) 13:30, 25 February 2018 (UTC)
Please leave the see also section there..... edit
It will be beneficial to the future of international standardization
Information relating to Ovex Suspension containing Mebendazole edit
Product information from Boots https://www.boots.com/ovex-suspension-30ml-family-pack-10068980
Information leaflet by Ovex https://www.medicines.org.uk/emc/files/pil.1766.pdf
Pharmaceutical page by emc https://www.medicines.org.uk/emc/product/1766/smpc
2.124.248.60 (talk) 17:13, 13 May 2019 (UTC)
Toxicity of Mebendazole (Toxicology Data Network) edit
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3232
Human Health Effects edit
Human Toxicity Excerpts
Drug Warnings
Populations at Special Risk
Probable Routes of Human Exposure
Animal Toxicity Studies edit
Non-Human Toxicity Excerpts
Non-Human Toxicity Values
Metabolism/Pharmacokinetics edit
Metabolism/Metabolites
Absorption, Distribution & Excretion
Biological Half-Life
Mechanism of Action
Interactions
2.124.248.60 (talk) 18:38, 13 May 2019 (UTC)
Regarding UK price in the "cost" subcategory. edit
Under the Cost subcategory there is this line: "In Australia 6 x 100mg costs approximately US$9 while in the UK this would cost around US$19.[20] and about US$5 in Europe." With the citation linking to an FT article locked behind a paywall. Currently in the UK Mebendazole under the Ovex brand (100mg x 4 tablet dose) are sold online for £6, £6 is about $8 US or just over $11 Australian.
(https://ayp.healthcare/ovex-family-pack-4-threadworm-treatment-tablets) for an example.
In pharmacies in the UK it is often cheaper, but I cannot give you an exact figure. So it seems as though if the $18 price is written in that FT article, it is either incorrect or out of date.
Giardiasis edit
There is no indication in the use of mebendazole for the treatment of giardia — Preceding unsigned comment added by 87.117.189.244 (talk) 17:39, 6 January 2022 (UTC)
- ? "In conclusion, the use of mebendazole, which is less toxic with no side-effects, is available and effective on Giardia intestinalis as well as intestinal nematodes, is recommended especially in the areas where giardiasis and intestinal nematodiasis are prevalent and overlap." Sadjjadi, S. M. (2001-06-01). "Comparative Clinical Trial of Mebendazole and Metronidazole in Giardiasis of Children". Journal of Tropical Pediatrics. 47 (3): 176–178. doi:10.1093/tropej/47.3.176. ISSN 0142-6338. Largoplazo (talk) 17:47, 6 January 2022 (UTC)