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Rating too low edit
We feel that the comment "this article is on a subject of low importance within molecular and cellular biology" is not adequate. Ephrins are becoming more and more important in cancer biology. A molecule active on Ephrin B4, subject of complex debate betweeen pharmaceutical firms, was discussed on September 4 at the International Association for the Study of Lung Cancer. Google has 419,000 pages on Ephrin. I suggest replacing "low importance" by "growing interest". Healthvalue 06:45, 6 September 2007 (UTC)
Please clarify edit
Please write a more clear introductory paragraph. Is it an article about ephrins or about their receptors? What do they do? Why a single article about both ephrines and eph receptors? The introduction gives a headache to a newbie reader. Best regards, --CopperKettle 08:56, 17 August 2009 (UTC)
- I've started a separate page for Ephrins in Russian Wiki. If anybody does a split here, notify me or find the page (Эфрины) by yourself and add the interwiki. Cheers. --CopperKettle 16:29, 28 August 2009 (UTC)
Although this page contains a general overview of Eph receptors and their biological function, the introduction required a lot of editing (and was requested to be edited by Wikipedia) to make it more coherent and more accessible to the general reader. Additionally, the subclasses of Ephs and ephrins were updated and expanded to provide a greater indication to the reader that the subclasses are distinct, even though they often have similar roles in biological functions. The general mechanism of Eph receptor activation was added to give the more scientifically-inclined reader the opportunity to understand how forward signaling by the Eph receptor was transmitted. The section on axon guidance was updated to correct a few errors and generalizations that did not belong in this section. — Preceding unsigned comment added by Armadaskier324 (talk • contribs) 22:43, 13 December 2011 (UTC)
Important Redirect edit
The page for "Ephrin receptor" was redirected to a page titled simply "Eph receptor" as receptors related to Eph are properly termed "Ephs" and not "Ephrin receptors"[1]. All discussion in the future should be contained on the "Eph Receptor" page.
Armadaskier324 (talk) 22:45, 13 December 2011 (UTC)
Incorrect Name edit
As has been mentioned above, but incorrectly reverted by another user, these proteins are Ephs or Eph receptors. They are not Ephrin receptors. Eph receptors name comes from "erythropoietin-producing hepatocellular receptors", not Ephrin receptors. Ephrins are another type of ligand/receptor (depends on your point-of-view) with another Wikipedia article dedicated to it, which bind Ephs. — Preceding unsigned comment added by Enozkan (talk • contribs) 03:40, 26 April 2016 (UTC)
References edit
- ^ Ephnomenclaturecommittee (1997). "Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee". Cell. 90 (3): 403–404. doi:10.1016/S0092-8674(00)80500-0. PMID 9267020.