Talk:Dobutamine

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Dobutamine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

what is dobutamine test? edit

Latest comment: 6 years ago3 comments3 people in discussion

Catecholamines reduce cardiac efficiency as they increase oxygen demand without nessesarily increasing output or efficiency. It is therefore not a good choice of drug for shock or heart failure. In this scenario it would only reproduce the undesirable effects of MI where adrenaline is produced. —Preceding unsigned comment added by 77.99.102.107 (talk) 13:40, 12 January 2008 (UTC)Reply

41.233.144.251 (talk) 12:36, 26 May 2009 (UTC) In small therapeutic doses, dobutamine can induce cardiac contraction alone, without an increase in heart rate, thus, improve cardiac function with little increase in oxygen demand.Reply

I also think that it's useful in ischemic heart disease, but I might be wrong.

There appears to be a typo: the hypertensive effects of dopamine are due to activity at alpha 1, not dopamine receptors — Preceding unsigned comment added by 66.243.219.231 (talk) 20:12, 14 August 2017 (UTC)Reply

GUC

Also important, is that at high doses, the antihypertensive effect can actually cause hypotension, which is dangerous is some cases- like in hypotension secondary to Right Ventricle STEMI, if fluid resuscitation fails to increase blood pressure, Dobutamine would be a poor choice, especially high doses of it. You'd want to use other inotropics.

"Since it does not act on dopamine receptors to inhibit the release of norepinephrine (another α1 agonist), dobutamine is less prone to induce hypertension than is dopamine."

Is this the wrong way around

dopamine receptors to cause the release of norepinephrine ....

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