Talk:CpG oligodeoxynucleotide

Latest comment: 25 days ago by Iridix in topic Would CpG Oligonucleotide be a better name

Untitled edit

JohnDoe 02:52, 14 August 2009 (UTC)

Would CpG Oligonucleotide be a better name edit

"CpG Oligonucleotide" seems the more widely used term - Are there any/many nondeoxy CpG Oligonucleotides ? - Rod57 (talk) 14:14, 6 April 2018 (UTC)Reply

The word "oligonucleotide" may refer to both "oligoribonucleotides" and "oligodeoxyribonucleotides". TLR9 receptors don't recognize RNA, but only dsDNA. Hence, the physiological effect of CpG oligos being accepted to be TLR9-mediated, it is correct to say "oligodeoxynucleotide", and not "oligonucleotide". Iridix (talk) 12:56, 25 April 2024 (UTC)Reply

Which one was FDA approved as a vaccine adjuvant edit

Which CpG ODN was FDA approved as a vaccine adjuvant ? When ? Type B or type A, and what drug name, structure etc ? - Rod57 (talk) 14:25, 6 April 2018 (UTC)Reply